Mubychem Group, established in 1976, is the pioneer manufacturer of Sodium Acetate, Pharmaceutical, Fragrance & Flavor chemicals in India. Mubychem Group has several manufacturing facilities spread across Gujarat and Mumbai India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Indonesia, Spain etc. |
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The participating units have one or more accreditations like FDA - GMP approval; ISO-9001 Certified; "REACH" Pre-registered; ISO-22000; Kosher Certified; Halal Certified; HACCP. We offer Pure & IP BP USP FCC Food Grade ACS AR Analytical Reagent Grades of Chemicals |
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Sodium Acetate BP Ph Eur USP IP ACS Analytical Reagent FCC Food Grade Manufacturers
Sodium Acetate IP Technical & Sodium Acetate Pure Grade
MSDS of Sodium Acetate Anhydrous Manufacturers
MSDS of Sodium Acetate Trihydrate BP USP FCC Food Grade ACS GR AR Analytical Reagent Manufacturers
Sodium Acetate
Anhydrous Trihydrate
CAS Number 127-09-3 & 6131-90-4, IP BP Ph. Eur. USP ACS AR LR FCC Food Grades
Sodium Acetate USP Grade Specifications
Sodium Acetate
USP
C2H3NaO2-3H2O -- 136.08
Assay
Sodium
Acetate contains three molecules of water of hydration, or is anhydrous. It
contains not less than 99.0 percent and not more than 101.0 percent of
C2H3NaO2, calculated on the dried basis.
Packaging and storage Preserve in tight containers.
Labeling
Label it
to indicate whether it is the trihydrate or is anhydrous. Where Sodium
Acetate is intended for use in hem dialysis, it is so labeled.
Identification A
solution responds to the test for Sodium and for Acetate.
pH: between 7.5 and
9.2, in a solution in carbon dioxide-free water containing the equivalent of
30 mg of anhydrous sodium acetate per mL.
Loss on drying Dry
at 120 to constant weight: the hydrous form loses between 38.0% and 41.0% of
its weight, and the anhydrous form loses not more than 1.0% of its weight.
Insoluble matter Dissolve the equivalent of 20 g of anhydrous sodium acetate in 150 mL of
water, heat to boiling, and digest in a covered beaker on a steam bath for 1
hour. Filter through a tarred filtering crucible, wash thoroughly, and dry at
105 : the weight of the residue does not exceed 10 mg (0.05%).
Chloride
A portion
equivalent to 1.0 g of anhydrous sodium acetate shows no more chloride than
corresponds to 0.50 mL of 0.020 N hydrochloric acid (0.035%).
Sulfate
A portion
equivalent to 10 g of anhydrous sodium acetate shows no more sulfate than
corresponds to 0.50 mL of 0.020 N sulfuric acid (0.005%).
Calcium and magnesium To 20 mL of a solution containing the equivalent of 10 mg of anhydrous
sodium acetate per mL add 2 mL each of 6 N ammonium hydroxide, ammonium
oxalate TS, and dibasic sodium phosphate TS: no turbidity is produced within
5 minutes.
Potassium
Dissolve
the equivalent of 3 g of anhydrous sodium acetate in 5 mL of water, add 1N
acetic acid drop wise until the solution is slightly acidic, and then add 5
drops of sodium cobalt nitrite TS: no precipitate is formed.
Aluminum: (where it
is labeled as intended for use in hem dialysis) the limit is 0.2΅ =g per g.
Heavy metalsthe
limit is 0.001%.
Organic volatile
impurities: meets the requirements.
Sodium Acetate Trihydrate BP Ph Eur Grade Specifications
Sodium Acetate BP
C2H3NaO2,3H2O
Action and use
Used in solutions for dialysis; excipient.
DEFINITION
Sodium ethanoate trihydrate.
Content
99.0 per cent to 101.0 per cent (dried
substance).
CHARACTERS
Appearance
Colourless crystals.
Solubility
Very soluble in water, soluble in ethanol (96 per
cent).
IDENTIFICATION
A.
1 ml of solution S (see Tests) gives reaction (b) of acetates.
B.
1 ml of solution S gives reaction (a) of sodium.
C.
Loss on drying (As shown in the Relevant Test).
TESTS
Solution S
Dissolve 10.0 g in carbon
dioxide-free water prepared from
distilled water R
and dilute to 100 ml
100 ml with the same solvent.
Appearance of
solution
Solution S is clear and colourless.
pH
7.5 to 9.0.
Dilute 5 ml of solution S to 10 ml with carbon
dioxide-free water.
Reducing substances
Dissolve 5.0 g in 50 ml of water,
then add 5 ml of dilute sulphuric
acid and 0.5 ml of 0.002 M potassium
permanganate. The pink colour persists
for at least 1 h. Prepare a blank in the same manner but without the
substance to be examined.
Chlorides
Maximum 200 ppm.
Sulphates
Maximum 200 ppm.
Aluminium
Maximum 0.2 ppm, if intended for use in the
manufacture of dialysis solutions.
Arsenic
Maximum 2 ppm, determined on 0.5 g.
Calcium and
magnesium
Maximum 50 ppm, calculated as Ca.
Heavy metals
Maximum 10 ppm.
Iron
Maximum 10 ppm, determined
on 10 ml of solution S.
Loss on drying
39.0 per cent to 40.5 per
cent, determined on 1.000 g by drying in an oven at 130C.
Sodium Acetate FCC US Food Grade Specifications
C2H3NaO2 Formula weight,
anhydrous 82.03
C2H3NaO2·3H2O Formula weight,
trihydrate 136.08
DESCRIPTION
Sodium Acetate occurs as
colorless, transparent crystals or as a granular, crystalline or white
powder. The anhydrous form is hygroscopic; the trihydrate effloresces in
warm, dry air. One gram of the anhydrous form dissolves in about 2 mL of
water; 1 g of the trihydrate dissolves in about 0.8 mL of water and in about
19 mL of alcohol.
Function: Buffer.
REQUIREMENTS
Identification: A 1:20 aqueous solution gives positive tests for
Sodium and for Acetate.
Assay: Not less than
99.0% and not more than 101.0% of C2H3NaO2 after drying.
Alkalinity Anhydrous: Not more than 0.2%; Trihydrate: Not more than 0.05%.
Lead: Not more than
2 mg/kg.
Loss on Drying: Anhydrous: Not more than 1.0%; Trihydrate: Between 36.0% and
41.0%.
Potassium Compounds: Passes test.
Sodium Acetate ACS Reagent Grade specifications
Sodium Acetate Anhydrous
CH3COONa
Formula Weight 82.03
CAS Number 127-09-3
REQUIREMENTS
Assay: 99.0%
C2H3O2Na
pH of a 5%
solution: 7.0-9.2 at 25C
MAXIMUM ALLOWABLE
Insoluble
matter: 0.01%
Loss on drying at 120C: 1.0%
Chloride
(Cl): 0.002%
Phosphate (PO4): 0.001%
Sulfate (SO4): 0.003%
Calcium
(Ca): 0.005%
Magnesium
(Mg): 0.002%
Heavy metals (as
Pb): 0.001%
Iron
(Fe): 0.001%
Sodium Acetate Trihydrate ACS specifications
American Chemical Society Reagent Grade
NaC2H3O2-3H2O
Formula Weight 136.08
CAS Number 6131-90-4
REQUIREMENTS
Assay: 99.0-101% NaC2H3O2-3H2O
pH of a 5%
solution: 7.5-9.2 at 25C
Substances reducing permanganate: Passes test
MAXIMUM ALLOWABLE
Insoluble
matter: 0.005%
Chloride (Cl): 0.001%
Phosphate (PO4): 5 ppm
Sulfate (SO4): 0.002%
Heavy metals (as Pb): 5 ppm
Iron
(Fe): 5 ppm
Calcium
(Ca): 0.005%
Magnesium
(Mg): 0.002%
Potassium
(K): 0.005%
Sodium Acetate BP Ph Eur, Sodium Acetate USP IP ACS AR Analytical Reagent FCC Food grade manufacturers at:
MUBYCHEM GROUP
CHINCHBUNDER, MUMBAI 400009, INDIA
TEL: (OFFICE)
91-22-23774610, 91-22- 23723564. 91-22-23728264
e-mail: info@mubychem.com
USA & Canadian Customers may e-mail: us@mubychem.com
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is Applicable.
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29-Apr-2022